A weak handshake can be an indication of increased frailty. Grip strength has been linked to dementia, cardiovascular diseases and mortality. Mark Peterson, a professor of physical medicine and rehabilitation at the University of Michigan, says grip strength correlates with changes in a person's DNA that indicate how fast they are aging. He suggests strength training. "People who have strong grip strength tend to have strong legs, backs and arms," says Mr. Peterson. Basically, people who work out tend to be stronger all over than people who don't. Do you or have you ever strength trained?

Swollen and painful fingers are the results of arthritis. The two most common types are osteoarthritis (OA) and rheumatoid arthritis (RA). RA usually affects both hands and often involves the joints where the fingers meet the hands. OA may affect a single hand or digit and often leads to bony overgrowths at the finger's middle or last joint. Stuart Kaplan M.D. is chief of rheumatology at Mount Sinai South Nassau in Oceanside, NY. He notes there are great drugs for RA called biologics that can change the course of the disease and stop it in its tracks if caught early enough. For OA, nonsteroidal anti-inflammatory drugs (NSAIDS) and anti-inflammatory creams help with the discomfort. Do you suffer from pain in your hands?

Yellow knuckle bumps are often deposits of fat called xanthomas. People who have them may have high levels of lipid in their blood. Xanthomas may signal diabetes, liver disease or an underactive thyroid. Please consult a doctor who will help tackle the problem of high lipid levels with a cholesterol-lowering drug. Were you aware of yellow knuckle bumps before this survey?

Nails that curve down and bulging fingertips are signs of possibly serious lung conditions. The most common are lung cancer, COPD and tuberculosis. People with symptoms are urged to see a doctor as soon as they notice a change since treatment may require speed. Have you ever been a caregiver for someone with COPD?

Black or brown streaks in a fingernail might be a mole or signs of infection. However, it can also indicate melanoma, the most deadly form of skin cancer. Nail melanoma is rare but much more deadly than skin melanoma. The nail may split, bleed or seep pus. It's important to diagnose early. See a doctor if you notice dark streaks in your nails. Change may go unnoticed by those who get regular manicures so give nails a good examination monthly. Were you aware of nail melanoma before taking this survey?